Charles Richet discovered more than a hundred years ago that injecting proteins into mammals will cause the development of allergies to those proteins. Subsequent exposure to those proteins will cause an allergic reaction that he termed – anaphylaxis. He was awarded the Nobel Prize for this work.
Let’s call it the Richet allergy model.
The US Dept. of Health and Human Services (HHS) charged the Institute of Medicine (IOM) with providing a thorough review of the current medical and scientific evidence on vaccines and vaccine adverse events.
The IOM has concluded in its 2011 report, using medical terminology, that:
FOOD PROTEINS PRESENT IN VACCINES CAUSE THE DEVELOPMENT OF FOOD ALLERGIES.
Document Pg. 65 (pdf pg. 94 ):
“Adverse events on our list thought to be due to IgE-mediated hypersensitivity reactions
Antigens in the vaccines that the committee is charged with reviewing do not typically elicit an immediate hypersensitivity reaction (e.g., hepatitis B surface antigen, toxoids, gelatin, ovalbumin, casamino acids).
However, as will be discussed in subsequent chapters, the above-mentioned antigens do occasionally induce IgE-mediated sensitization in some individuals and subsequent hypersensitivity reactions, including anaphylaxis.”
In normal life, proteins we consume orally are digested and converted into amino acids before they are absorbed into the bloodstream. The injection needle bypasses this process and allows the injection of proteins, exposing them directly to the blood. The immense consequences of this capability cannot be understated.
The injection needle has enabled vaccines to become one of the greatest successes of modern medicine.
But it comes at a huge cost that is not yet fully appreciated. It is extremely important to understand and resolve these issues of vaccine/injection safety immediately before more people are injured.
Vaccines work, in part, by causing allergy to viruses and bacteria
When viral or bacterial proteins are injected into the body, the body develops an allergy specific to that virus or bacteria.
The article below shows that 100% of the adults vaccinated with an inactivated virus flu shot developed anti-influenza antibodies. Immunoglobulin E or IgE is another name for these antibodies.
Inactivated virus vaccines basically contain viral proteins specific to that virus. Developing antibodies or IgE specific to a protein is called sensitization or development of an allergy to that protein. So everyone who got a flu shot became allergic to those viruses. This is a good thing and protects you from a viral infection. If the body is exposed to these viruses, the viruses attach to the antibodies and are attacked by the immune system.
Smith-Norowitz TA, Wong D, Kusonruksa M, Norowitz KB, Joks R, Durkin HG, Bluth MH. Long Term Persistence of IgE Anti-Influenza Virus Antibodies in Pediatric and Adult Serum Post Vaccination with Influenza Virus Vaccine. Int J Med Sci 2011; 8(3):239-244. doi:10.7150/ijms.8.239. Available from http://www.medsci.org/v08p0239.htm
When any other protein is injected, the body does the same thing. It treats the protein as a virus protein, develops an allergy and attacks it when subsequently exposed to it.
Adjuvants
Adjuvants are substances added to vaccines that increase the sensitivity of the immune system.
When using an adjuvant, very little viral protein is needed to obtain an immune response. So large number of vaccine doses can be made with very little viral protein when using adjuvants.
But by the same token, the immune system is also sensitized and responds to even small quantities of any other protein injected along with the vaccine, when adjuvants are used.
Mechanism of food allergy development
When food proteins are injected in to the blood stream, a type I hypersensitivity reaction against an allergen, encountered for the first time, causes a response in a type of immune cell called a TH2 lymphocyte, which belongs to a subset of T cells that produce a cytokine called interleukin-4 (IL-4). These TH2 cells interact with other lymphocytes called B cells, whose role is the production of antibodies. Coupled with signals provided by IL-4, this interaction stimulates the B cell to begin production of a large amount of a particular type of antibody known as IgE that are specific to the food proteins. Secreted IgE circulates in the blood and binds to an IgE-specific receptor (a kind of Fc receptor called FcεRI) on the surface of other kinds of immune cells called mast cells and basophils, which are both involved in the acute inflammatory response. The IgE-coated cells, at this stage are sensitized to the allergen (food proteins). [1] [2]
In other words, an allergic reaction occurs to the foods that contain the food proteins which were present in the vaccine. Red seaweed is a food source for shellfish. Vaccines can induce an allergy to red seaweed proteins. Consuming shellfish (or any seafood that is contaminated with red seaweed proteins) will result in an allergic reaction.
The same mechanism holds for any other protein that is injected into the body.
Food Allergies
How are food proteins exposed to the blood stream?
Vaccines, injections, tick bites and poor digestion due to acid reducing medications such as proton pump inhibitors (PPI). Food (plant and animal) proteins such as egg, milk (casein), yeast, gelatin, red seaweed (agar), vegetable oils ( as part of Polysorbate 80) are present in various vaccines (CDC’s vaccine ingredients list).
Vitamin K1 injections also contain vegetable oil and/or animal fats.
Vegetable oils are oils from plant sources and can include peanut oil, tree nut oil, sesame oil etc.
So allergies to peanuts, tree nuts, sesame and other allergens listed above could be traced to such injections/vaccines.
Tick bites result in the injection of a protein called alpha-gal (which is present in red meat) into the blood stream.[3]
When acidity in the stomach is reduced by acid reducing medications, food proteins are not broken down. They travel to the intestine intact and get absorbed into the blood stream.[4]
In all cases, the food proteins thus introduced into the blood stream can result in developing allergies to those food items.
Gelatin in vaccines was proved to be the cause of gelatin allergy.
protein during influenza virus immunization
BY N. YAMANE AND H. UEMURA
In the laboratory, scientists induce food allergy in mice by injecting them with food proteins along with alum as an adjuvant. The same way vaccines inject food proteins along with adjuvants into humans.
Example of inducing food allergy in mice:
So we have seen various methods by which food proteins can be injected into the body, whether in mice or humans and the result is the same – development of food allergy.
Predicting the rate of egg allergy in the US based on the Richet allergy model
A typical flu shot contains 15 mcg of hemagglutinin (HA) protein per virus type and 0.5 mcg of ovalbumin protein. About 60% of US children who receive a flu shot get sensitized to the HA protein. The result is the immune system attacks HA proteins on subsequent exposure giving protection against the flu virus. One can expect 60/(15/0.5)=2% of those who receive the flu shot to get sensitized to the ovalbumin protein. The result is the immune system attacks the ovalbumin protein on subsequent exposure, giving egg allergy.
Indeed the estimated prevalence of egg allergy in children in the US is ~2% of the population. http://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM371815.pdf
http://www.cdc.gov/flu/about/season/effectivenessqa-2013-14.htm
Asthma
There are two mechanisms by which vaccines/injections can cause asthma.
Polysorbate 80 is used in the laboratory to cause lung injury in sheep for research.
Many vaccines contain Polysorbate 80 and can be causing lung injury in humans resulting in asthma.
We saw in the previous section that injected proteins result in development of allergy to those proteins. What if the injected protein resembles a protein that is part of our body?
The immune system can be sensitized to the protein and begins attacking parts of our own body – an autoimmune disorder results.
Many vaccines contain human WI-38 human diploid lung fibroblasts or human embryonic lung cultures. If the immune system is sensitized to proteins in such lung tissue, it begins attacking our lung tissue. The result could be asthma.
This study shows that unvaccinated children had zero occurrence of asthma compared to 1.8-4.6% for vaccinated children.
Vaccination Status and Health in Children and Adolescents
This study states:
Childhood Vaccinations and Risk of Asthma
“The strongest evidence in support of a possible association between vaccination and asthma comes from a prospective study of a cohort of children born in 1977 in Christchurch, New Zealand. In that study there was no evidence of asthma after 5 to 10 years of follow-up among 23 children who received neither pertussis nor oral polio vaccine, whereas asthma developed in >20% of 1184 children who had been vaccinated.”
Some pertussis vaccines (DTaP) contain Polysorbate 80.
Type I Diabetes
One of the HiB vaccines approved by the FDA contains Modified Mueller Miller medium. The other two HiB vaccines do not.
Click to access excipient-table-2.pdf
Modified Mueller Miller medium contains pancreatic digest.
Based on the Richet allergy model, one would predict that the pancreatic digest in the HiB vaccine could cause autoimmunity to the pancreas, thus attacking pancreatic cells resulting in the autoimmune disorder – Type I diabetes.
Association between type 1 diabetes and Hib vaccine
Causal relation is likely
Please see the diabetes mellitus section in:
Vaccination may be Associated with Autoimmune Diseases
Since not all HiB vaccines contain pancreatic digest, one can expect the mixed results that are published.
Further, many other vaccines contain Modified Mueller, Miller medium. So HiB may not be the only vaccine to cause Type I diabetes.
Latex Allergy
Multi-dose injection/vaccination vials may have a stopper/cap made of natural rubber latex.
Injection needles are inserted into the cap to draw the medicine.
Risk of anaphylaxis to latex from injection obtained from rubber-stoppered vials
Single-dose syringes may have a latex tip cap.
http://latexallergyresources.org/news/2013-14-flu-vaccine-information
Either way, needles and vaccine/injection contents are contaminated with latex.
When the latex is injected along with the vaccine/injection content, again per the Richet allergy model, people develop latex allergy.
Ulcerative colitis
Any intramuscular vaccine/injection needle will tear off muscle tissue and deposit it along with the vaccine contents. One muscle protein is tropomyosin. Tropomyosin is found in the brain and intestines also. A person can develop sensitization to this tropomyosin protein, resulting in the immune system attacking the body’s tissues that contain tropomyosin. In other words, an autoimmune disorder results. When the immune system attacks the intestines, the result is ulcerative colitis. Likewise, autoimmune brain disorders are also possible.
Das, KM; Dasgupta, A; Mandal, A; Geng, X (1993). “Autoimmunity to cytoskeletal protein tropomyosin. A clue to the pathogenetic mechanism for ulcerative colitis”. J Immunol 150 (6): 2487–2493. PMID 8450225.
A simple estimate of the amount of tropomyosin that may be torn off and deposited by an intramuscular shot.
Muscle density is 1.09g/ml
20% of that is muscle protein 0.212 g/ml
3% of that is tropomyosin 0.00636 g/ml
25 gauge 5/8 inch needle used for intramuscular injection has an outer diameter of 0.5mm and so a volume of 3 cubic mm.
or 0.003 ml.
If during injection, muscle volume corresponding to the entire volume of the needle was torn off and deposited as a blob, it would have a volume of 0.003 ml.
Tropomyosin in that volume = 2e-5 g. or 20 mcg.
A flu shot in comparison contains 15 mcg of viral protein.
The study below shows 100% of those who received the flu shot developed allergy to the virus (anti-influenza IgE).
Smith-Norowitz TA, Wong D, Kusonruksa M, Norowitz KB, Joks R, Durkin HG, Bluth MH. Long Term Persistence of IgE Anti-Influenza Virus Antibodies in Pediatric and Adult Serum Post Vaccination with Influenza Virus Vaccine. Int J Med Sci 2011; 8(3):239-244. doi:10.7150/ijms.8.239. Available from http://www.medsci.org/v08p0239.htm
So with 20 mcg of tropomyosin injected, everyone who receives an intramuscular shot can expect to develop allergy to tropomyosin.
Since muscles are soft, the needle probably does not bore a clean hole. A lot of the muscle probably gets squeezed out of the way.
If not for this detail, perhaps a lot more of us will probably be dealing with autoimmune disorders associated with tropomyosin.
Due to cross reaction, allergy to tropomyosin can also result in allergy to certain seafoods that contain tropomyosin.
Eczema
Like the above, intradermal and intramuscular injections/vaccines tear off skin tissues and deposit them with the injection/vaccine contents. The result is the patient develops sensitization to skin proteins. The immune system attacks skin tissue that contains skin proteins resulting in autoimmune skin disorders such as eczema.
Why has the FDA approved these vaccines?
I asked the FDA if they have determined a safe level of these proteins that can be present in vaccines. Their response:
“There is not, as you describe it, an FDA determined safe amount of a potentially allergenic ingredient contained in a vaccine. The FDA reviews vaccine composition in its entirety to ensure the safety and efficacy of the vaccine.”
So the FDA has not studied if there is a safe level for proteins present in vaccines.
They do not specify a safe level and therefore cannot test for it either.
In clinical trials before a vaccine is approved, the FDA and the manufacturers look for “Solicited Adverse Events” which include local injection site reactions (pain, redness, and swelling) and general adverse events, (fatigue, fever, gastrointestinal symptoms, headache, arthralgia, myalgia, and urticaria) within 7 days after vaccination.
The immune system takes a few weeks to develop an immune response and provide protection against the viral/bacterial proteins. The FDA and CDC will advise you to take the flu shots early to provide time for this process. For the exact same reason, development of allergies to the injected undesirable proteins will also take a few weeks. The FDA and the manufacturers are not looking for allergy and autoimmune disorders (not part of the “solicited adverse events”). The FDA and the manufacturers are also not waiting long enough to check for these adverse events.
If the FDA and the manufacturers neither wait long enough for the adverse events to develop nor check for such adverse events at all, they are not going to find them. So the vaccines get approved.
C-section – A contributing factor
“In the gastrointestinal tract of babies born by c-section, there is a pattern of “at risk” microorganisms that may cause them to be more vulnerable to developing the antibody Immunoglobulin E, or IgE, when in contact with allergens” – Christine Cole Johnson, Ph.D., MPH, chair of Henry Ford Department of Health Sciences.[5]
Protein absorption in newborns
If newborns are fed proteins, they can absorb the intact proteins into the bloodstream for a few days. During those few days, feeding the newborn any protein (e.g. infant formula), other than those present in the colostrum, can be dangerous. Especially so, if the birth was via C-section thus priming the baby for development of IgE.
Hydrolyzed (proteins already broken down) infant formula may be safe per NIH Guideline 39.
Prevention or mitigation
A diet enriched with cocoa prevents IgE synthesis in a rat allergy model.
Administer only one vaccine or injection at a time. Wait a few weeks before the next one. Vaccines/injections have multiple food proteins and multiple adjuvants. Adjuvants improve the efficacy of the immune response. However, they can also increase the probability of developing allergies to the food proteins in the vaccine. Today, kids get five shots in one sitting. Multiple food proteins and adjuvants being simultaneously administered can significantly increase the probability of developing food allergies.
For the first week after birth, infant formula should be avoided. Or, choose infant formula with hydrolyzed proteins if absolutely required, to reduce risk.
More prevention tips suggested by reader Victoria:
Avoid skin prick allergy tests. There is the risk of exposing injected allergens to the bloodstream, where they can cause sensitization and development of allergies. Use blood tests instead. If you already have an allergy, the skin prick test can also act as an allergy booster shot.
Use oral Vitamin K1 instead of an injection.
Common questions
If vaccines cause food allergies, why do anaphylaxis events occur more rarely compared to the number of patients diagnosed with food allergies?
Vaccine anaphylaxis rates are unlikely to be related to food allergy development rates.
The amount of food proteins in vaccines vary widely. For example, measles, mumps and rubella
vaccine (MMR) has 4x-40x more gelatin than DTaP.
Development of food allergy requires only trace quantities of food protein as Nakayama et al., have
found. DTaP causes the development of gelatin allergy and subsequent MMR administration results in anaphylaxis. When MMR is administered first, one would expect that it is more likely to cause the
development of gelatin allergy. Subsequent DTaP administration however does not result in
anaphylaxis, most likely due to the small quantity of gelatin present in DTaP. This is probably the
reason people who are allergic to egg can still get flu shots without developing anaphylaxis. However, the flu shot could be acting as an egg allergy booster shot.
micro-lesions in the mouth?
hundreds of millions of years. The result is that organisms sensitive enough to develop food allergies through micro lesion exposure would have been naturally eliminated during the evolution process. Therefore, one can expect that food allergy in humans due to micro lesion exposure would be rare. Vaccines and injections are of course a different matter. Children receive five vaccine shots in one sitting. Nothing in nature prepares a human child for this load of food proteins with multiple powerful adjuvants entering the body, all at one time.
Food Allergy Causes 